Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
0.200 Therapeutic group RGD Glycogen synthase kinase 3 beta regulates ethanol consumption and is a risk factor for alcohol dependence. 30188517 2018
Entrez Id: 130497
Gene Symbol: OSR1
OSR1
0.010 Biomarker group BEFREE Childhood ADHD, ODD, CD, and depression increase the risk of developing substance-related disorders. 28647007 2017
Entrez Id: 4988
Gene Symbol: OPRM1
OPRM1
0.300 Biomarker group CTD_human Synthetic and Receptor Signaling Explorations of the Mitragyna Alkaloids: Mitragynine as an Atypical Molecular Framework for Opioid Receptor Modulators. 27192616 2016
Entrez Id: 8850
Gene Symbol: KAT2B
KAT2B
0.100 GeneticVariation group GWASCAT KAT2B polymorphism identified for drug abuse in African Americans with regulatory links to drug abuse pathways in human prefrontal cortex. 26202629 2016
Entrez Id: 288
Gene Symbol: ANK3
ANK3
0.010 Biomarker group BEFREE This led us to hypothesize that ANK3 might also be associated with stress-related psychopathology such as posttraumatic stress disorder (PTSD), as well as disorders of the externalizing spectrum such as antisocial personality disorder and substance-related disorders that are etiologically linked to impulsivity and temperamental disinhibition. 23796624 2013
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.020 GeneticVariation group BEFREE The brain derived neurotrophic factor (BDNF) locus has been implicated in psychiatric and substance related disorders. 23624487 2013
Entrez Id: 23114
Gene Symbol: NFASC
NFASC
0.100 GeneticVariation group GWASCAT NCK2 is significantly associated with opiates addiction in African-origin men. 23533358 2013
Entrez Id: 8440
Gene Symbol: NCK2
NCK2
0.100 GeneticVariation group GWASCAT NCK2 is significantly associated with opiates addiction in African-origin men. 23533358 2013
Entrez Id: 1268
Gene Symbol: CNR1
CNR1
0.300 Biomarker group CTD_human Association between a cannabinoid receptor gene (CNR1) polymorphism and cannabinoid-induced alterations of the auditory event-related P300 potential. 21513772 2011
Entrez Id: 63876
Gene Symbol: PKNOX2
PKNOX2
0.100 GeneticVariation group GWASCAT The nuclear transcription factor PKNOX2 is a candidate gene for substance dependence in European-origin women. 21298047 2011
Entrez Id: 1138
Gene Symbol: CHRNA5
CHRNA5
0.300 Biomarker group CTD_human Low ethanol concentration alters CHRNA5 RNA levels during early human development. 20438829 2010
Entrez Id: 1129
Gene Symbol: CHRM2
CHRM2
0.300 Biomarker group CTD_human Altered neural cholinergic receptor systems in cocaine-addicted subjects. 20393457 2010
Entrez Id: 114788
Gene Symbol: CSMD3
CSMD3
0.300 Biomarker group CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010
Entrez Id: 1962
Gene Symbol: EHHADH
EHHADH
0.300 Biomarker group CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010
Entrez Id: 9271
Gene Symbol: PIWIL1
PIWIL1
0.300 Biomarker group CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010
Entrez Id: 5583
Gene Symbol: PRKCH
PRKCH
0.300 Biomarker group CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010
Entrez Id: 64131
Gene Symbol: XYLT1
XYLT1
0.300 Biomarker group CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010
Entrez Id: 55742
Gene Symbol: PARVA
PARVA
0.300 Biomarker group CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010
Entrez Id: 1826
Gene Symbol: DSCAM
DSCAM
0.300 Biomarker group CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010
Entrez Id: 9128
Gene Symbol: PRPF4
PRPF4
0.300 Biomarker group CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010
Entrez Id: 57733
Gene Symbol: GBA3
GBA3
0.300 Biomarker group CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010
Entrez Id: 167465
Gene Symbol: ZNF366
ZNF366
0.300 Biomarker group CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010
Entrez Id: 140733
Gene Symbol: MACROD2
MACROD2
0.300 Biomarker group CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010
Entrez Id: 143098
Gene Symbol: MPP7
MPP7
0.300 Biomarker group CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010
Entrez Id: 9748
Gene Symbol: SLK
SLK
0.300 Biomarker group CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010